Quadruple Automation Services

💊
Industries Pharmaceutical Manufacturing
💊

Pharmaceutical Manufacturing
Solutions

QAS delivers MES, PLC/SCADA, ERP integration and AI analytics purpose-built for pharmaceutical manufacturing — FDA 21 CFR Part 11, GMP batch records, serialisation and end-to-end quality management, with 24/7 onsite and remote support.

FDA 21 CFR Part 11
GMP Batch Records
Electronic Batch Release
Serialisation & Track & Trace
SAP PP / QM Integration
Deviation & CAPA Workflow
Cleanroom Monitoring
24/7 Onsite Support
Industry Challenges

What Pharma Plants Face Every Day

Pharmaceutical manufacturing operates under the strictest regulatory frameworks of any industry. A single batch record error, an audit observation or a data integrity breach can halt production, trigger recalls or result in consent decrees. We understand the stakes — and we build systems that guarantee compliance while maximising output.

Manual paper batch records creating data integrity risks
FDA audit observations due to uncontrolled electronic records
Batch-to-batch variability with no real-time process control
Serialisation and track-and-trace integration gaps
SAP batch management disconnected from shop-floor events
Deviation and CAPA workflows managed in spreadsheets
Cleanroom environmental monitoring not linked to batches
Lack of real-time OEE visibility across filling and packaging lines
FDA Warning Letter
Consent decree & production halt risk
Batch Record Error
Recall + regulatory fine exposure
Data Integrity Breach
ALCOA+ violation — loss of approval
Serialisation Failure
Market withdrawal & supply disruption
Manual CAPA Tracking
Months to close, repeat deviations
No Real-time Monitoring
Batch failures found after release
Our Solutions

What We Build for Pharma Plants

End-to-end automation, compliance and digitalisation capabilities — all delivered by a single experienced partner who understands GMP from the ground up

Pharmaceutical MES (GMP)

FDA 21 CFR Part 11 compliant MES built for pharmaceutical lines — electronic batch records, production order management, in-process controls, EBR sign-off and full audit trail from dispensing to packaging.

Electronic Batch Records (EBR) FDA 21 CFR Part 11 Compliant In-Process Controls (IPC) Dispensing & Weighing OEE per Line Electronic Batch Release
Learn More

PLC & SCADA / DCS

GMP-compliant PLC and DCS programming for granulation, blending, filling, lyophilisation and packaging lines. SCADA/HMI with 21 CFR Part 11 electronic signatures, audit trail and access control.

Siemens / Allen-Bradley / DeltaV GMP-Compliant HMI / SCADA 21 CFR Part 11 e-Signatures Cleanroom EMS Integration Alarm Management Historian & Audit Trail
Learn More

ERP Integration (SAP)

Bidirectional SAP PP, MM, QM and WM integration with your pharma MES. Batch management, goods receipt, usage decisions, inventory reconciliation and production order confirmations — all automated and audit-trailed.

SAP Batch Management PP Production Orders QM Usage Decisions MM Goods Receipt / Issue WM Warehouse Movements Real-time Sync & Audit Trail
Learn More

IIoT & Process Connectivity

Connect granulators, tablet presses, coaters, lyophilisers, filling lines and CIP/SIP systems via OPC-UA and MQTT. Real-time process parameter capture linked to batch records — every value, every timestamp.

Tablet Press & Granulator Data Lyophiliser Signal Capture CIP/SIP Automation OPC-UA / MQTT Process Parameter Linking Environmental Sensor Integration
Learn More

Quality & Compliance

Electronic deviation management, CAPA workflow, change control and risk management integrated with your MES and ERP. Full ALCOA+ data integrity — attributable, legible, contemporaneous, original and accurate.

Deviation Management CAPA Workflow Change Control Risk Management (ICH Q9) ALCOA+ Data Integrity Serialisation & Track & Trace
Learn More

AI Analytics & Predictive

Predictive batch yield modelling, OEE dashboards, right-first-time analytics and equipment predictive maintenance. AI process optimization for critical process parameters — blend endpoint, granule PSD and dissolution prediction.

Batch Yield Prediction Right-First-Time Analytics OEE & Downtime Dashboards Predictive Maintenance CPP / CQA Monitoring Management KPI Reporting
Learn More
Functionalities Covered

Every Function, Covered

A full catalogue of pharmaceutical-specific manufacturing functions we have designed, built and deployed in GMP production environments

Batch & Production Mgmt

Production order download from SAP
Batch record creation & management
Dispensing & weighing instructions
In-process control (IPC) scheduling
Yield calculation & reconciliation
Batch hold / release workflow
Scrap & rework recording
Shift & line OEE calculation

Quality & Compliance

Electronic batch records (EBR)
FDA 21 CFR Part 11 audit trail
In-process quality checks & specs
Deviation capture & classification
CAPA management workflow
Change control (electronic)
Right-first-time (RFT) tracking
OOS / OOT investigation workflow

Traceability & Serialisation

Full batch genealogy tree
Serialisation (DSCSA / EU FMD)
Track & trace aggregation
Barcode / 2D matrix scanning
Raw material lot traceability
Finished goods batch linkage
Recall & containment workflow
Label generation & verification

Maintenance & Asset

Predictive maintenance alerts
PM scheduling & work orders
Breakdown recording & RCA
Calibration management (IQ/OQ/PQ)
MTTR / MTBF tracking
SAP PM notification auto-raise
Spare parts management
Maintenance KPI dashboards

Process & Equipment Connect

Tablet press & granulator data
Coating pan parameter capture
Lyophiliser cycle monitoring
Filling line speed & reject data
CIP/SIP cycle verification
Autoclave cycle data capture
Vision & serialisation camera
Environmental monitoring sensors

ERP & System Integration

SAP PP production confirmation
SAP MM goods issue / receipt
SAP QM usage decisions
SAP WM warehouse movements
SAP PM work order update
Batch & routing synchronisation
Inventory reconciliation real-time
LIMS bidirectional integration

Reporting & Analytics

Real-time OEE dashboards
Batch summary & trend reports
Deviation frequency Pareto
Yield loss root-cause analysis
Right-first-time trend tracking
Management KPI packs (auto)
Custom Power BI / Grafana
AI predictive batch outcome

Regulatory & Compliance

FDA 21 CFR Part 11 compliance
EU Annex 11 alignment
GMP Annex 15 validation support
GAMP 5 categorisation approach
ALCOA+ data integrity controls
Electronic signature workflow
User access & role management
Full IQ / OQ / PQ documentation
Support

Support That Never Stops — Just Like Your Batches

Pharmaceutical manufacturing runs around the clock. Our support model is built to match — onsite GMP-trained engineers on your shift pattern, remote monitoring 24/7, and planned maintenance that fits your production schedule.

Tier 1

Onsite Resident Engineer

A dedicated QAS GMP-trained engineer stationed at your plant, working your shift rotations. Available on the production floor, not at a help desk 500 miles away.

Dedicated GMP-trained QAS engineer at your site
Shift-pattern aligned (days / nights / weekends)
Line-side troubleshooting & diagnostics
System configuration & enhancement on-site
Operator and maintenance team coaching
First point of escalation to remote team
24/7 LIVE
Tier 2

Remote 24/7 Monitoring & Support

Round-the-clock remote system monitoring. Our engineers watch MES health, batch progress, ERP integration and SCADA alarms in real time — and respond before issues become batch failures.

24/7/365 helpdesk coverage
Real-time MES, SCADA & ERP monitoring
Remote access for diagnosis and fix
< 15 min response for critical production issues
Escalation to onsite engineer within 2 hours
Monthly system health and SLA reports
Tier 3

Planned & Preventive Support

Scheduled maintenance visits, software updates, validation change controls and quarterly system reviews planned around your batch schedules and production shutdown periods.

Quarterly system health & performance reviews
Planned software updates with GMP change control
Optimization visits aligned to shutdown periods
Enhancement backlog management & sprints
Annual disaster recovery and backup testing
Full validation documentation maintenance

Ready to Transform Your Pharma Plant?

From a single line EBR implementation to a full plant GMP digitalisation programme — talk to our pharma specialists and get a tailored proposal with compliance roadmap and ROI estimates.

Book a Free Plant Assessment All Industries
Chat with us